Glucose-induced self-assembly and phase separation in hydrophilic triblock copolymers and the governing mechanism
Divya Patel, Amit K. Bhojani, Debes Ray, Dheeraj K. Singh, Sanyukta Bhattacharjee, Debabrata Seth, Vinod K. Aswal, Ketan Kuperkar, Pratap Bahadur
Abstract
) increases in the presence of glucose, thereby indicating Cur solubility enhancement for the Pluronic® micelles. Various kinetics models were employed, demonstrating a drug release profile that enables this approach to be used as an ideal platform for drug delivery.
Topics & Concepts
CopolymerEthylene oxideMicellePoloxamerCloud pointDynamic light scatteringPropylene oxideChemical engineeringPhase (matter)ChemistryOxideNeutron scatteringMaterials scienceSmall-angle neutron scatteringAmphiphilePolymer chemistryAnalytical Chemistry (journal)ScatteringChromatographyPolymerOrganic chemistryNanotechnologyAqueous solutionOpticsPhysicsEngineeringNanoparticleSurfactants and Colloidal SystemsAdvanced Polymer Synthesis and CharacterizationPolymer composites and self-healing