FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma
Yuanfang Zhai, Chengyuan Shan, Zhang Haoyu, Pengzhou Kong, Ling Zhang, Yanqiang Wang, Xiaoling Hu, Xiaolong Cheng
Topics & Concepts
Gene knockdownCancer researchDownregulation and upregulationKLF4Wnt signaling pathwayCancer stem cellEpithelial–mesenchymal transitionCisplatinBiologyCadherinCancerStem cellCellCell cultureSignal transductionCell biologyChemotherapySOX2Transcription factorGeneGeneticsBiochemistryWnt/β-catenin signaling in development and cancerCancer-related gene regulationKruppel-like factors research