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A CRISPR-enabled fluorometric biosensor for the sensitive detection of heparin antidote protamine based on programmable nuclease Cas12a

Zhirun Ji, Zhaoyang Shang, Muhammad Sohail, Pei Wang, Bingzhi Li, Xing Zhang, Guoxiang Chen

2022Sensors and Actuators B Chemical25 citationsDOI

Topics & Concepts

ProtamineDetection limitChemistryNucleaseDNAMultiplexBiosensorBiochemistryTrans-activating crRNABioanalysisChromatographyBiophysicsBiologyHeparinCRISPRCas9BioinformaticsGeneCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA regulation and disease
A CRISPR-enabled fluorometric biosensor for the sensitive detection of heparin antidote protamine based on programmable nuclease Cas12a | Litcius