Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein
Zhen Wah Tan, Wei-Ven Tee, Firdaus Samsudin, Enrico Guarnera, Peter J. Bond, Igor N. Berezovsky
Topics & Concepts
DruggabilityAllosteric regulationSpike ProteinSpike (software development)CoronavirusComputational biologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyCoronavirus disease 2019 (COVID-19)ChemistryVirologyGeneticsMedicineComputer scienceReceptorGeneSoftware engineeringInfectious disease (medical specialty)DiseasePathologySARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsCOVID-19 Clinical Research Studies