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Olfactomedin-4 deletion exacerbates DSS-induced colitis through a matrix metalloproteinase-9-dependent mechanism

Xinyu Wang, Shenghui Chen, Jinghua Wang, Yishu Chen, Yanjun Guo, Qinqiu Wang, Zhening Liu, Hang Zeng, Chengfu Xu

2023International Journal of Biological Sciences18 citationsDOIOpen Access PDF

Abstract

Notch1 signaling.

Topics & Concepts

Ulcerative colitisColitisProinflammatory cytokineMatrix Metalloproteinase 3Inflammatory bowel diseaseMetalloproteinaseKnockout mouseMatrix metalloproteinaseDownregulation and upregulationMedicineCancer researchImmunologyInflammationChemistryPathologyInternal medicineBiochemistryDiseaseGeneReceptorInflammatory Bowel DiseaseDrug Transport and Resistance MechanismsInflammatory mediators and NSAID effects
Olfactomedin-4 deletion exacerbates DSS-induced colitis through a matrix metalloproteinase-9-dependent mechanism | Litcius