Litcius/Paper detail

Biphase Ionic Hydrogels with Ultrasoftness and High Conductivity for Bio-Ionotronics

Bingsen Wang, Fagui Dong, Xisheng Sun, Yanan Bu, Haonan Wang, Dawei Tang, Lin Li

2025ACS Nano24 citationsDOI

Abstract

Achieving stable bioelectronic interfaces is hindered by inherent mechanical–electrochemical mismatches, limiting long-term device functionality in dynamic tissues. Current hydrogel-based bio-ionotronic devices face a fundamental trade-off: soft hydrogels lack sufficient ionic carriers, while ionic hydrogels compromise softness due to high cross-linking density. Here, we developed a biphasic ionic hydrogel (BIH) by integrating microgel-rich ionic reservoirs (microgel phase) into a continuous hydrogel matrix (CH phase) via hydrogen bonds. The microgel phase and CH phase of BIH work synergistically, reducing cross-linking density while maintaining the ion monomer content of the hydrogel. This synergistic structure decouples ionic storage from mechanical compliance, enabling ultrasoftness (2 kPa) and high ionic conductivity (8.55 S m –1 ), surpassing conventional ionic hydrogels. By tuning the microgel content, we increased the polymer network’s characteristic length, facilitating ion diffusion while maintaining structural integrity and reducing interfacial impedance. Demonstrations in real-time electromyography and mechanical motion sensing validated its potential for soft bioelectronics.

Topics & Concepts

Self-healing hydrogelsIonic conductivityMaterials scienceConductivityIonic bondingNanotechnologyChemical engineeringChemistryIonElectrolytePolymer chemistryPhysical chemistryOrganic chemistryElectrodeEngineeringAdvanced Sensor and Energy Harvesting MaterialsDielectric materials and actuatorsHydrogels: synthesis, properties, applications