Molecular testing for lung adenocarcinoma: Is it time to adopt a “plasma‐first” approach?
Maisam Makarem, Natasha B. Leighl
Abstract
There is growing evidence that plasma cell‐free DNA testing can aid in the diagnosis of targetable alterations at diagnosis in patients with advanced nonsquamous lung carcinoma. A plasma‐first approach will facilitate access to precision medicine, with studies suggesting that nearly 60% of patients could benefit compared with the current approach of tissue profiling alone.
Topics & Concepts
MedicineLungOncologyAdenocarcinomaPrecision medicineLung cancerInternal medicineIntensive care medicinePathologyBioinformaticsCancer researchCancerBiologyCancer Genomics and DiagnosticsLung Cancer Treatments and MutationsViral-associated cancers and disorders