A physical basis for quantitative ChIP-sequencing
Bradley M. Dickson, Rochelle L. Tiedemann, Alison A. Chomiak, Evan M. Cornett, Robert M. Vaughan, Scott B. Rothbart
Abstract
uantitative ChIP-sequencing (siQ-ChIP). A number of changes in community practice of ChIP-Seq, data reporting, and analysis are motivated by this work.
Topics & Concepts
Chromatin immunoprecipitationChipHistoneComputer scienceComputational biologySpike (software development)ChromatinBiologyGeneticsDNATelecommunicationsGeneGene expressionSoftware engineeringPromoterGenomics and Chromatin DynamicsEpigenetics and DNA MethylationRNA modifications and cancer