Direct and Selective Synthesis of Adipic and Other Dicarboxylic Acids by Palladium‐Catalyzed Carbonylation of Allylic Alcohols
Ji Yang, Jiawang Liu, Yao Ge, Weiheng Huang, Helfried Neumann, Ralf Jackstell, Matthias Beller
Abstract
Abstract A general and direct synthesis of dicarboxylic acids including industrially important adipic acid by palladium‐catalyzed dicarbonylation of allylic alcohol is reported. Specifically, the combination of PdCl 2 and a bisphosphine ligand (HeMaRaphos) promotes two different carbonylation reactions with high activity and excellent selectivity.
Topics & Concepts
CarbonylationPalladiumChemistryAllylic rearrangementCatalysisAdipic acidSelectivityLigand (biochemistry)AlcoholOrganic chemistryDicarboxylic acidCarbon monoxideReceptorBiochemistryAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and CatalysisCatalytic Cross-Coupling Reactions