Indium promoted C(sp<sup>3</sup>)–P bond formation by the Domino A<sup>3</sup>-coupling method – a combined experimental and computational study
Suman Das, Parveen Rawal, Jayeeta Bhattacharjee, Ajitrao Devadkar, Kuntal Pal, Puneet Gupta, Tarun K. Panda
Abstract
An efficient catalytic process for the synthesis of α-aminophosphonates is developed by a one-pot three-component reaction in the presence of In complexes at room temperature. DFT based mechanistic studies of the catalytic reactions are reported.
Topics & Concepts
IndiumCatalysisDominoCoupling (piping)Coupling reactionChemistryComponent (thermodynamics)Computational chemistryCombinatorial chemistryMaterials scienceOrganic chemistryPhysicsMetallurgyThermodynamicsOrganophosphorus compounds synthesisAsymmetric Hydrogenation and CatalysisSulfur-Based Synthesis Techniques