Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review
Jelena Roganović, Nina Petrović
Abstract
Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases. Based on ncRNAs' suitability for salivary biomarkers and their involvement in neuropathic pain and tissue regeneration signaling pathways, the present narrative review aims to highlight the potential clinical applications of ncRNAs in oral inflammatory diseases, with an emphasis on salivary diagnostics, regenerative dentistry, and precision medicine for neuropathic orofacial pain.
Topics & Concepts
Neuropathic painEpigeneticsmicroRNABioinformaticsMedicineNarrative reviewLong non-coding RNABurning mouth syndromeNeuroscienceRNABiologyGeneIntensive care medicineDentistryGeneticsPharmacologyCancer-related molecular mechanisms researchSalivary Gland Disorders and FunctionsPeriodontal Regeneration and Treatments