Litcius/Paper detail

Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery

Paris S. Hamm, Frances E. Homan, Shyleigh A. Good, Jennifer Hathaway, Ashley E. Clements, Evelyn G. Haugh, Lindsay K. Caesar

2025Natural Product Reports14 citationsDOIOpen Access PDF

Abstract

, redox chemical properties and biomineralization). This article highlights the significance of caves and mines as reservoirs of microbial diversity, the potential impact of their bioactive compounds on the fields of healthcare and biotechnology, and the significant challenges that must be overcome to access and harness the biotechnological potential of subterranean microbial communities. Additionally, it emphasizes the conservation efforts needed to protect these delicate ecosystems, ensuring the preservation of both ancient traditions and tomorrow's medicines.

Topics & Concepts

CaveNatural productNatural (archaeology)Product (mathematics)BiologyEcologyGeographyArchaeologyMathematicsBiochemistryGeometryGenomics and Phylogenetic StudiesMicrobial Community Ecology and PhysiologyProtist diversity and phylogeny