Synthesis of morpholine derivatives using the Castagnoli-Cushman reaction as BACE1 inhibitors: Unexpected binding activity of cyclic thioamides
Lorenzo Calugi, Elena Lenci, Riccardo Innocenti, Andrea Trabocchi
Topics & Concepts
MorpholineChemistryThioamideStereochemistryEnzymeDocking (animal)CatalysisCombinatorial chemistryOrganic chemistryNursingMedicineSynthesis and Biological ActivityChemical synthesis and alkaloidsQuinazolinone synthesis and applications