Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery
Sarah K. Madden, Laura S. Itzhaki
Topics & Concepts
KEAP1Mechanism (biology)UnderpinningDrug discoverySmall moleculeComputational biologyChemistryNanotechnologyBiologyEngineeringBiochemistryMaterials sciencePhysicsTranscription factorCivil engineeringGeneQuantum mechanicsGenomics, phytochemicals, and oxidative stressSynthesis and Biological Evaluation