Pt Nanoparticles Confined by Zirconium Metal–Organic Frameworks with Enhanced Enzyme-like Activity for Glucose Detection
Hanhan Wang, Jun Zhao, Chuang Liu, Yuping Tong, Weiwei He
Abstract
. Because of the confinement effect of mesopores, the Pt particles with an average diameter of 3.8 nm are formed and dispersed throughout the pores of the UiO-66 particle. The Pt/UiO-66 composites show efficient oxidase- and peroxidase-like activity. Both the oxidase- and peroxidase-like activities are dependent on the Pt percentage. Pt/UiO-66-6% exhibits enhanced peroxidase-like activity, ∼3.9 times higher than that of commercial Pt/C with 10 wt % Pt. We propose that the construction of Pt/UiO-66 increased the utilization efficiency and stability of Pt NPs and provided more active sites for catalytic reactions. Using the peroxidase-like activity of Pt/UiO-66, a colorimetric method that can be used for actual blood glucose detection was developed for the specific detection of glucose with a limit of detection of 0.033 mM.