Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling
Zhenzhou Zhang, Jianqiong Tang, Jiawei Song, Mengshi Xie, Ying Liu, Zhaojie Dong, Xiaoyan Liu, Xueting Li, Mi-Wen Zhang, Yihang Chen, Hongyu Shi, Jiuchang Zhong
Topics & Concepts
FibrosisMyocardial fibrosisAngiotensin IIDownregulation and upregulationCardiac fibrosisInternal medicineInflammationEndocrinologyMedicineOxidative stressGene knockdownEnosReceptorChemistryApoptosisNitric oxideNitric oxide synthaseBiochemistryGeneApelin-related biomedical researchCardiovascular, Neuropeptides, and Oxidative Stress ResearchHormonal Regulation and Hypertension