Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium
Mihaela-Loredana Vlad, Răzvan Gheorghiţă Mareş, Gabriel Jakobsson, Simona‐Adriana Manea, Alexandra-Gela Lazar, Mihai Bogdan Preda, Mirel Adrian Popa, Maya Simionescu, Alexandru Şchiopu, Adrian Manea
Topics & Concepts
NADPH oxidaseInflammasomeReactive oxygen speciesPriming (agriculture)NOX4ChemistryPharmacologyCaspase 1Cell biologyMedicineBiologyBiochemistryReceptorBotanyGerminationS100 Proteins and AnnexinsCardiac Ischemia and ReperfusionCardiac Fibrosis and Remodeling