Exploring a novel thiazole derivatives hybrid with fluorinated-indenoquinoxaline as dual inhibitors targeting VEGFR2/AKT and apoptosis inducers against hepatocellular carcinoma with docking simulation
Moustafa S. Abusaif, Ahmed Ragab, Eman A. Fayed, Yousry A. Ammar, Ayah M. H. Gowifel, Soha Osama Hassanin, Ghada E. Ahmed, Nirvana A. Gohar
Topics & Concepts
ChemistryHepatocellular carcinomaProtein kinase BThiazoleVEGF receptorsApoptosisCancer researchDocking (animal)InducerCombinatorial chemistryBiochemistryStereochemistryGeneBiologyNursingMedicineSynthesis and biological activityCancer Mechanisms and TherapyClick Chemistry and Applications