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Clinical characteristic and epidemiological features of SARS CoV‐2 disease patients from a COVID‐19 designated hospital in New Delhi

Sonal Saxena, Vikas Manchanda, Tanu Sagar, Nazia Nagi, Oves Siddiqui, Abhishek Yadav, Nitin Arora, Faria Hasan, Kavita Meena, Pradeep Bharti, Neha Rana, Sikander Hayat, Sanchita Tuteja, Ajeet Kumar Yadav, Devyani Puri, Palak Pumma, Khyati, Ananya Arora, Jainandra, Sunidhi Shreya, Suresh Kumar, Nandini Sharma

2021Journal of Medical Virology14 citationsDOI

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection is rapidly evolving as a serious global pandemic. The present study describes the clinical characteristics of SARS CoV-2 infection patients. The samples were subjected to reverse-transcription polymerase chain reaction or Rapid Antigen test for diagnosis of SARS CoV-2. A cohort of 3745 patients with confirmed diagnosis of SARS CoV-2 infection in a tertiary care center in New Delhi, India were included in this study. Data were collected from offline and online medical records over a period of 6 months. Amongst 3745 SARS CoV-2 infected patients, 2245 (60%) were symptomatic and 1500 (40%) were asymptomatic. Most common presenting symptom was cough (49.3%) followed febrile episodes (47.1%), breathlessness (42.7%), and sore throat (35.1%). Cough along with breathlessness (24.1) was the most common combination of symptoms followed by fever with cough (22.7). The most common comorbidity found among symptomatic group was diabetes (42.5%) followed by hypertension (21.4%) and chronic kidney disease (18%). Comorbidities like diabetes mellitus, chronic diseases of lungs, heart, and kidneys were found to be common in symptomatic group and this was found to be statistically significant (p < .05). COVID-19 is an evolving disease and data from our study help in understanding the clinic-epidemiological profile of patients.

Topics & Concepts

MedicineAsymptomaticEpidemiologySore throatComorbidityCohortInternal medicineDiseaseDiabetes mellitusPandemicKidney diseasePediatricsSurgeryCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)EndocrinologyCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19
Clinical characteristic and epidemiological features of SARS CoV‐2 disease patients from a COVID‐19 designated hospital in New Delhi | Litcius