Ruthenium(II) Complexes of an Imidazole Carboxamido Ligand for Base-Free Transfer Hydrogenation in Air
Richard J. Citta, Brandon L. Koteles, Brenda Delgado-Perez, Benny C. Chan, Steven E. Kalman
Abstract
Two half-sandwich ruthenium(II) complexes of an imidazole-2-carboxamido ligand have been synthesized and characterized by nuclear magnetic resonance spectroscopy, elemental analysis, and, in one case, single-crystal X-ray diffraction. Both complexes serve as precatalysts for base-free transfer hydrogenation under aerobic conditions. A substrate scope study with a range of ketones and aldehydes was performed, and a preliminary investigation into the mechanism of catalysis was undertaken. These complexes represent relatively rare examples of transfer hydrogenation catalysts that do not require an inert atmosphere and an exogenous base.
Topics & Concepts
ChemistryRutheniumImidazoleTransfer hydrogenationCatalysisLigand (biochemistry)Noyori asymmetric hydrogenationInert gasBase (topology)Single crystalSubstrate (aquarium)Polymer chemistryPhotochemistryCombinatorial chemistryOrganic chemistryCrystallographyBiochemistryOceanographyMathematicsReceptorGeologyMathematical analysisAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisOrganometallic Complex Synthesis and Catalysis