Addendum: Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus
Joana Isidro, Vítor Borges, Miguel Pinto, Daniel Sobral, João Dourado Santos, Alexandra Nunes, Verónica Mixão, Rita Ferreira, Daniela Santos, Sílvia Duarte, Luı́s Vieira, Maria José Borrego, Maria Sofia Núncio, Isabel Lopes de Carvalho, Ana Pelerito, Rita Cordeiro, João Paulo Gomes
Abstract
On 10 June 2022, a new nomenclature system for the monkeypox virus (MPXV) clades and lineages was proposed by Happi et al. 1 that defined the Clade 1 (former Congo Basin) and Clades 2 and 3 (both comprising the former West African clade). Our study, published online in Nature Medicine on 24 June 2022, relied on this nomenclature. Later, on 12 August 2022, the World Health Organization, together with a group of global experts, revised and agreed on the new naming convention for MPXV clades in which the previously proposed Clades 1, 2 and 3 are now designated Clades I, IIa and IIb, respectively 2 . The initial proposal by Happi et al. was subsequently updated 1 as well as the final corresponding publication 3 .