Mechanochemical cocrystallization to improve the physicochemical properties of chlorzoxazone
Parag Roy, Animesh Ghosh
Abstract
Cocrystals of chlorzoxazone prepared by mechanochemical cocrystallization with picolinic acid to improve the physicochemical properties.
Topics & Concepts
ChlorzoxazoneCocrystalPicolinic acidChemistryMechanochemistryMaterials scienceOrganic chemistryMoleculeHydrogen bondCytochrome P450EnzymeCYP2E1Crystallography and molecular interactionsPhenothiazines and Benzothiazines Synthesis and ActivitiesCrystallization and Solubility Studies