A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
Yixuan Ye, Rommell B. Noche, Natalia Szejko, Cameron Both, Julián Acosta, Audrey C. Leasure, Stacy Brown, Kevin N. Sheth, Thomas M. Gill, Hongyu Zhao, Guido J. Falcone
Topics & Concepts
Genome-wide association studyMendelian randomizationMedicineObesityDiabetes mellitusGenetic associationPleiotropyGenetic correlationInternal medicineSingle-nucleotide polymorphismPhenotypeBiologyGeneticsGenetic variationGenetic variantsGeneEndocrinologyGenotypePopulationEnvironmental healthNutrition and Health in AgingFrailty in Older AdultsFolate and B Vitamins Research