Case Report: Rhabdomyolysis in a Patient with COVID-19: A Proposed Diagnostic-Therapeutic Algorithm

José Gabriel Solís, Alejandra Esquivel Pineda, Paolo Alberti‐Minutti, Alejandra Albarrán‐Sánchez

2020American Journal of Tropical Medicine and Hygiene28 citationsDOI Open Access PDF

Abstract

COVID-19 represents the greatest health challenge of modern years. The spectrum of illness comprises respiratory and non-respiratory manifestations. We report the case of an adult man with COVID-19 who presented with rhabdomyolysis as a principal extrapulmonary manifestation. Our patient presented with dyspnea, fever, and muscle pain. After a comprehensive approach, the diagnosis of COVID-19 and rhabdomyolysis was made. He developed acute kidney injury requiring renal replacement therapy without reversibility, despite optimal treatment. We performed a literature search for similar cases, discuss the potential mechanisms implied, and propose a diagnostic-therapeutic algorithm.

Topics & Concepts

RhabdomyolysisMedicineCoronavirus disease 2019 (COVID-19)Intensive care medicineTherapeutic approachSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Acute kidney injuryRespiratory system2019-20 coronavirus outbreakAlgorithmInternal medicinePathologyComputer scienceDiseaseOutbreakInfectious disease (medical specialty)Muscle and Compartmental DisordersLong-Term Effects of COVID-19Inflammatory Myopathies and Dermatomyositis