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Synthesis and Characterization of Enantiopure Chiral Bis NHC-Stabilized Edge-Shared Au<sub>10</sub> Nanocluster with Unique Prolate Shape

Renee W. Y. Man, Hong Xun Yi, Sami Malola, Shinjiro Takano, Tatsuya Tsukuda, Hannu Häkkinen, Masakazu Nambo, Cathleen M. Crudden

2022Journal of the American Chemical Society79 citationsDOI

Abstract

Herein we report the first chiral Au10 nanoclusters stabilized by chiral bis N-heterocyclic carbene (bisNHC) ligands. ESI-MS and single-crystal X-ray crystallography confirmed the molecular formula to be [Au10(bisNHC)4Br2](O2CCF3)2. The chiral Au10 nanocluster adopts a linear edge-shared tetrahedral geometry with a prolate shape. DFT calculations provide insight into the electronic structure, optical absorption, and circular dichroism (CD) characteristics of this unique Au10 nanocluster. CD spectra demonstrate chirality transfer from the chiral bisNHC ligand to the inner Au10 nanocluster core. Examination of ESI-MS and UV–vis spectra show that cluster [Au9(bisNHC)4Br]Br2 is formed initially and then transformed into the Au10 nanocluster in solution.

Topics & Concepts

NanoclustersEnantiopure drugChemistryChirality (physics)CrystallographyCircular dichroismCarbeneCluster (spacecraft)Prolate spheroidEnantioselective synthesisCatalysisOrganic chemistryPhysicsSymmetry breakingChiral symmetry breakingClassical mechanicsComputer scienceQuantum mechanicsProgramming languageNambu–Jona-Lasinio modelNanocluster Synthesis and ApplicationsPharmacological Effects and Toxicity StudiesOrganometallic Complex Synthesis and Catalysis
Synthesis and Characterization of Enantiopure Chiral Bis NHC-Stabilized Edge-Shared Au<sub>10</sub> Nanocluster with Unique Prolate Shape | Litcius