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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L. Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula Gónzález-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, Eungi Kim, Xiaotian Zhang, Joshua M. Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J.H. Ryan, Mónica L. Guzmán, Jolanta Grembecka, Tomasz Cierpicki

2021Nature Chemical Biology67 citationsDOIOpen Access PDF

Topics & Concepts

Domain (mathematical analysis)Ring (chemistry)Small moleculeComputational biologyChemistryCell biologyBiologyBiochemistryOrganic chemistryMathematical analysisMathematicsEpigenetics and DNA MethylationMicrotubule and mitosis dynamicsCancer-related gene regulation
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