Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model
Sofia Reis Brandão, Ana Reis-Mendes, Pedro Domíngues, José Alberto Duarte, Maria de Lourdes Bastos, Félix Carvalho, Rita Ferreira, Vera Marisa Costa
Topics & Concepts
CardiotoxicityPharmacologyDoxorubicinMitochondrionCitric acid cycleMalate dehydrogenaseOxidative stressBiologyBiochemistryChemistryInternal medicineMedicineChemotherapyEnzymeChemotherapy-induced cardiotoxicity and mitigationMitochondrial Function and PathologyATP Synthase and ATPases Research