Systematic Review and Meta-Analysis on the Value of Chest CT in the Diagnosis of Coronavirus Disease (COVID-19): <i>Sol Scientiae, Illustra Nos</i>
Hugo J.A. Adams, Thomas C. Kwee, Derya Yakar, Michael D. Hope, Robert M. Kwee
Abstract
Diagnostic accuracy studies on chest CT in COVID-19 suffer from methodologic quality issues. Chest CT appears to have a relatively high sensitivity in symptomatic patients at high risk of COVID-19, but it cannot exclude COVID-19. Specificity is poor. These data, along with other local factors such as COVID-19 prevalence, available real-time reverse transcriptase-polymerase chain reaction tests, staff, hospital, and CT scanning capacity, can be useful to healthcare professionals and policy makers to decide on the utility of chest CT for COVID-19 detection in the hospital setting.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusMeta-analysisBetacoronavirusCoronavirus InfectionsValue (mathematics)DiseaseRadiologyPathologyInfectious disease (medical specialty)StatisticsOutbreakMathematicsCOVID-19 diagnosis using AIRadiomics and Machine Learning in Medical ImagingCOVID-19 Clinical Research Studies