Photo-Thermo-Mechanochemical Approach to Synthesize Quinolines via Addition/Cyclization of Sulfoxonium Ylides with 2-Vinylanilines Catalyzed by Iron(II) Phthalocyanine
Luyao Liu, Jingyang Lin, Mingxuan Pang, Huile Jin, Xiaochun Yu, Shun Wang
Abstract
A novel photo-thermo-mechanochemical approach to assembling quinolines catalyzed by iron(II) phthalocyanine has been realized for the first time. This transformation features a cost-efficient catalytic system and operational simplicity, is free of solvent, and shows good substrate tolerance, providing a green alternative to existing thermal approaches. Mechanistic experiments demonstrate that the in-situ-formed secondary amine may be the key intermediate for the further cyclization/aromatization process.
Topics & Concepts
ChemistryCatalysisAromatizationPhthalocyanineCombinatorial chemistrySubstrate (aquarium)Amine gas treatingOrganic chemistryOceanographyGeologyCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry MethodsOxidative Organic Chemistry Reactions