Arterial thromboembolism associated with COVID-19 and elevated D-dimer levels
Karan Garg, Michael E. Barfield, Michael Pezold, Mikel Sadek, Neal S. Cayne, Joanelle Lugo, Thomas S. Maldonado, Todd Berland, Caron Rockman, Glenn R. Jacobowitz
Abstract
The novel coronavirus 2019 (SARS-CoV-2) was first identified in January 2020 and has since evolved into a pandemic affecting >200 countries. The severity of presentation is variable and carries a mortality between 1% and 3%. We continue to learn about the virus and the resulting acute respiratory illness and hypercoagulability; however, much remains unknown. In our early experience in a high-volume center, we report a series of four cases of acute peripheral artery ischemia in patients with COVID-19 in the setting of elevated D-dimer levels.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)D-dimerSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicCoronavirus2019-20 coronavirus outbreakRespiratory systemCardiologyPeripheralInternal medicineIntensive care medicineEmergency medicineVirologyDiseaseOutbreakInfectious disease (medical specialty)COVID-19 Clinical Research StudiesVenous Thromboembolism Diagnosis and ManagementCOVID-19 and healthcare impacts