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Photobiocatalytic benzylic C–H acylation enabled by the synergy of a thiamine-dependent enzyme, an organophotocatalyst and hydrogen-atom transfer

Xichao Peng, Jianqiang Feng, Fulu Liu, Wen-Zheng Xie, Hailong Sun, Yuanyuan Xu, Ming Yang, Zhongqiu Xing, Yu Zheng, Binju Wang, Yi‐Tao Long, Xiaoqiang Huang

2025Nature Synthesis14 citationsDOI

Topics & Concepts

AcylationThiamineHydrogen atomEnzymeChemistryHydrogenStereochemistryBiochemistryOrganic chemistryCatalysisGroup (periodic table)Alcoholism and Thiamine DeficiencyAmino Acid Enzymes and MetabolismRadical Photochemical Reactions
Photobiocatalytic benzylic C–H acylation enabled by the synergy of a thiamine-dependent enzyme, an organophotocatalyst and hydrogen-atom transfer | Litcius