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Mirau-based line-field confocal optical coherence tomography

Arnaud Dubois, Weikai Xue, Olivier Levecq, Pavel Bulkin, Anne-Lise Coutrot, Jonas Ogien

2020Optics Express26 citationsDOIOpen Access PDF

Abstract

Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique in which A-scans are acquired in parallel through line illumination with a broadband laser and line detection with a line-scan camera. B-scan imaging at high spatial resolution is achieved by dynamic focusing in a Linnik interferometer. This paper presents an LC-OCT device based on a custom-designed Mirau interferometer that offers similar spatial resolution and detection sensitivity. The device has the advantage of being more compact and lighter. In vivo imaging of human skin with a resolution of 1.3 µm × 1.1 µm (lateral × axial) is demonstrated over a field of 0.9 mm × 0.4 mm (lateral × axial) at 12 frames per second.

Topics & Concepts

Optical coherence tomographyOpticsInterferometryConfocalImage resolutionTomographyResolution (logic)Coherence (philosophical gambling strategy)Line (geometry)Preclinical imagingMaterials sciencePhysicsComputer scienceIn vivoArtificial intelligenceBiotechnologyMathematicsQuantum mechanicsBiologyGeometryOptical Coherence Tomography ApplicationsAdvanced Fluorescence Microscopy TechniquesPhotoacoustic and Ultrasonic Imaging
Mirau-based line-field confocal optical coherence tomography | Litcius