MiRNA-766-3p inhibits gastric cancer via targeting COL1A1 and regulating PI3K/AKT signaling pathway
Yu‐Jie Ding, Mengyuan Zhang, Sheng Hu, Caiyun Zhang, Yue Zhou, Ming Han, Jingjing Li, Fulong Li, Hongmei Ni, Sheng-Quan Fang, Qilong Chen
Abstract
The miR-766-3p can inhibit the progression of gastric cancer by targeting COL1A1 and regulating the PI3K/AKT signal pathway. It could be a potential therapy option for the GC.
Topics & Concepts
microRNAPI3K/AKT/mTOR pathwayProtein kinase BCancerCancer researchBiologySignal transductionLuciferaseWestern blotComputational biologyBioinformaticsGeneCell biologyBiochemistryGeneticsTransfectionMicroRNA in disease regulationCircular RNAs in diseasesRNA modifications and cancer