A New Approach to Model Sporadic Alzheimer’s Disease by Intracerebroventricular Streptozotocin Injection in APP/PS1 Mice
Sally Kelliny, Liying Lin, Isaac Bul Deng, Jing Xiong, Fiona H. Zhou, Mohammed Al‐Hawwas, Larisa Bobrovskaya, Xin‐Fu Zhou
Topics & Concepts
Genetically modified mouseStreptozotocinNeuroinflammationTransgeneAmyloid (mycology)Oxidative stressDementiaEndocrinologyInternal medicineAmyloid betaMedicineAmyloid precursor proteinDiseaseAlzheimer's diseaseNeurosciencePharmacologyBiologyPathologyDiabetes mellitusBiochemistryGeneAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesMedicinal Plants and Neuroprotection