Exact site frequency spectra of neutrally evolving tumors: A transition between power laws reveals a signature of cell viability
Einar Bjarki Gunnarsson, Kevin Leder, Jasmine Foo
Topics & Concepts
PopulationMutation rateBirth–death processExponential growthPower lawStatisticBranching processSpectrum (functional analysis)Statistical physicsMathematicsLimitingPopulation sizePhysicsStochastic processSpectral lineWhite noiseStatisticsMutationPopulation modelStochastic modellingPower (physics)Expected valueSpectral densityLine (geometry)BiologyCellFractal and DNA sequence analysisCancer Genomics and DiagnosticsMathematical Biology Tumor Growth