Non-neoplastic colorectal disease biopsies: evaluation and differential diagnosis
Michelle Moore, Roger Feakins, Gregory Y. Lauwers
Abstract
A wide variety of non-neoplastic conditions may be encountered on colorectal biopsy encompassing idiopathic, infectious, vascular and immune-mediated aetiologies. Although interpretation of such biopsies may be challenging, appreciation of the dominant pattern of injury and subsequent host response may allow for a more focused histological diagnosis in the correct clinical and endoscopic setting. This article aims to provide a systematic, methodical approach to the assessment of such biopsies, concentrating mainly on diagnoses other than inflammatory bowel disease.
Topics & Concepts
MedicineInflammatory bowel diseaseNeoplastic diseaseBiopsyDifferential diagnosisMedical diagnosisPathologyDiseaseMicroscopic ColitisInflammatory Bowel DiseaseCeliac Disease Research and Management