Photoredox-catalyzed direct C(sp<sup>2</sup>)–H difluoromethylation of enamides or heterocycles with [bis(difluoroacetoxy)iodo]benzene
Yun Zhao, Yan Zhang, Yating Liu, Tong‐Hao Zhu, Jie Wu
Abstract
A photoredox-catalyzed direct C(sp 2 )–H difluoromethylation of enamides and heterocycles is accomplished by using easily accessible [bis(difluoroacetoxy)iodo]benzene as the CF 2 H source.
Topics & Concepts
ChemistryBenzeneCatalysisMedicinal chemistryCombinatorial chemistryOrganic chemistryFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsCatalytic C–H Functionalization Methods