The clinical importance of overweight or obesity on tumor recurrence in papillary thyroid carcinoma
Jung Min Kim
Abstract
BACKGROUND: Obesity is known to common, preventable, and modifiable cause of carcinogenesis. Obesity may be associated with the risk and prognosis of papillary thyroid carcinoma (PTC), but the results of studies are controversial. We studied whether overweight or obesity would be associated with poor prognoses, such as tumor recurrence in PTC patients. METHODS: PTC patients at a single institution were retrospectively reviewed. RESULTS: 5% with and without overweight or obesity, respectively (P=0.008 by log-rank test, median follow-up period: 10.5 years). However, this association was also lost on multivariate analysis adjusting for poor prognosis predictors of recurrence. CONCLUSIONS: Overweight or obesity might be associated with poor prognosis factors. However, they might not be associated with tumor recurrences of PTC.