Electrochemical remote C(sp<sup>3</sup>)–H thiocyanation
Xin‐Yu Pang, Hui He, Xiangrui Meng, Lin‐Bao Zhang, Shao‐Fei Ni, Ming Li, Weisi Guo
Abstract
An electrochemical thiocyanation of distal C(sp 3 )–H bonds based on amidyl radical-mediated 1,5-HAT has been developed. The transformation is highly site-selective and compatible with primary, secondary, and tertiary sulfonamides, and bioactive derivatives.
Topics & Concepts
ChemistryElectrochemistryCombinatorial chemistryPrimary (astronomy)Medicinal chemistryPhysical chemistryElectrodePhysicsAstronomySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods