The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2
Chunjie Meng, Jun Zhan, Delin Chen, Genze Shao, Hongquan Zhang, Wei Gu, Jianyuan Luo
Topics & Concepts
BiologyDeubiquitinating enzymeCell growthUbiquitinTranscription factorProgrammed cell deathCell biologyProteaseCellProteasomeBiochemistryApoptosisGeneEnzymeFerroptosis and cancer prognosisUbiquitin and proteasome pathwaysRNA modifications and cancer