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Potential nanoparticle applications for prevention, diagnosis, and treatment of COVID‐19

Sydney Kusumoputro, Shannon Tseng, Jonathan Tse, Christian Au, Candice Lau, Xiang Wang, Tian Xia

2020View16 citationsDOIOpen Access PDF

Abstract

Abstract The coronavirus disease 2019 (COVID‐19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses an unprecedented challenge to establish effective methods of prevention and treatment. Nanotechnology has shown excellent potential in its ability to fight a variety of healthcare problems due to nanomaterials’ unique physicochemical properties and controlled nano‐bio interactions. Expanding their application to a wide‐range of upstream and downstream approaches is necessary to fight COVID‐19. At different stages of this virus‐caused disease, nanotechnology could offer promising solutions, including a way to combat the large number of fatalities caused by a late‐stage cytokine storm. This mini‐review provides an overview of the recent studies regarding nanoparticles’ applications in vaccines, personal protective equipment, sterilization of contaminated environments, diagnostic testing, and cytokine reduction treatment in combating COVID‐19.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Cytokine stormCoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicNanotechnology2019-20 coronavirus outbreakIntensive care medicineRisk analysis (engineering)DiseaseMedicineComputer scienceInfectious disease (medical specialty)VirologyMaterials sciencePathologyOutbreakSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies