Pathobionts: mechanisms of survival, expansion, and interaction with host with a focus on <i>Clostridioides difficile</i>
Harish Chandra, Krishna Kant Sharma, Olli H. Tuovinen, Xingmin Sun, Pratyoosh Shukla
Abstract
and the recent findings on the roles of immune cells such as iTreg cells, Th17 cells, innate lymphoid cells, and cytokines in protection against pathobionts. The review calls for adoption of innovative tools and cutting-edge technologies in clinical diagnostics and therapeutics to provide insights in identification and quantification of pathobionts.
Topics & Concepts
ClostridioidesBiologyMicrobiomeInnate immune systemImmune systemImmunologyDiseaseInnate lymphoid cellIdentification (biology)Computational biologyBioinformaticsMicrobiologyMedicinePathologyBotanyClostridium difficile and Clostridium perfringens researchGut microbiota and healthHelicobacter pylori-related gastroenterology studies