Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions
Dhirendra K. Simanshu, Mark R. Philips, John F. Hancock
Topics & Concepts
BiologyDimerObligateCell biologyFunction (biology)KinaseDomain (mathematical analysis)SH3 domainBiochemistryProto-oncogene tyrosine-protein kinase SrcMathematicsNuclear magnetic resonanceMathematical analysisEcologyPhysicsProtein Kinase Regulation and GTPase SignalingReceptor Mechanisms and SignalingProtein Structure and Dynamics