Photoinduced copper-catalyzed enantioselective coupling reactions
Liangliang Song, Lingchao Cai, Lei Gong, Erik V. Van der Eycken
Abstract
polar and radical mechanisms, exploring general and practical strategies for the regio-, enantio- and diastereoselective assembly of stereogenic centers is of significant value but remains highly problematic. The integration of photocatalysis with asymmetric copper catalysis could provide appealing access to the development of new reaction pathways and structurally diverse chiral compounds, and extend the boundaries of radical chemistry. This review summarizes recent advances in photoinduced copper-catalyzed enantioselective coupling reactions, and discusses the mechanistic aspects.
Topics & Concepts
Enantioselective synthesisCopperCatalysisCoupling (piping)ChemistryCoupling reactionCombinatorial chemistryPhotochemistryMaterials scienceOrganic chemistryMetallurgyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques