Gastrodin alleviates cisplatin nephrotoxicity by inhibiting ferroptosis via the SIRT1/FOXO3A/GPX4 signaling pathway
Cai-Wei Qiu, Bo Chen, Huifeng Zhu, Ying-Lan Liang, Linshen Mao
Topics & Concepts
Lipid peroxidationChemistryGPX4PharmacologyReactive oxygen speciesProgrammed cell deathBiochemistryGlutathione peroxidaseOxidative stressApoptosisMedicineSuperoxide dismutaseChemotherapy-induced organ toxicity mitigationFerroptosis and cancer prognosisNatural Compounds in Disease Treatment