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COVID-19 vaccination strategies depend on the underlying network of social interactions

Helena A. Saunders, Jean‐Marc Schwartz

2021Scientific Reports21 citationsDOIOpen Access PDF

Abstract

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, different mitigation and management strategies limiting economic and social activities have been implemented across many countries. Despite these strategies, the virus continues to spread and mutate. As a result, vaccinations are now administered to suppress the pandemic. Current COVID-19 epidemic models need to be expanded to account for the change in behaviour of new strains, such as an increased virulence and higher transmission rate. Furthermore, models need to account for an increasingly vaccinated population. We present a network model of COVID-19 transmission accounting for different immunity and vaccination scenarios. We conduct a parameter sensitivity analysis and find the average immunity length after an infection to be one of the most critical parameters that define the spread of the disease. Furthermore, we simulate different vaccination strategies and show that vaccinating highly connected individuals first is the quickest strategy for controlling the disease.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Vaccination2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyData scienceComputer scienceMedicineOutbreakDiseasePathologyInfectious disease (medical specialty)COVID-19 epidemiological studiesSARS-CoV-2 and COVID-19 ResearchMisinformation and Its Impacts