<i>In vivo</i> targeted delivery of antibodies into cancer cells with pH-responsive cell-penetrating poly(disulfide)s
Yulong Kong, Kui Zeng, Ying Zhang, Jinning Shao, Jiaqi Yan, Jia‐Yu Liao, Wenchao Wang, Xiaoyang Dai, Qinjie Weng, Shao Q. Yao, Su Zeng, Linghui Qian
Abstract
Acidity-activated cell-penetrating poly(disulfide)s ( CPD IMD ) were developed for in vivo targeted delivery of antibodies into cancer cells.
Topics & Concepts
In vivoDisulfide bondAntibodyChemistryCancer cellCellIn vitroCancer researchCancerBiophysicsBiochemistryMedicineBiologyImmunologyInternal medicineBiotechnologyRNA Interference and Gene DeliveryViral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy research