SIRT3 protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway
Tongshuai Chen, Chang Ma, Guanqi Fan, Hui Liu, Lin Xie, Jingyuan Li, Na Li, Shujian Wang, Mei Zeng, Yun Zhang, Peili Bu
Topics & Concepts
SenescenceSIRT3MatrigelUmbilical veinTransfectionDownregulation and upregulationAcetylationAngiogenesisEndothelial stem cellCell biologyEndothelial dysfunctionEndocrinologyChemistryBiologyInternal medicineCell cultureCancer researchMedicineIn vitroSirtuinBiochemistryGeneGeneticsSirtuins and Resveratrol in MedicineAntioxidant Activity and Oxidative StressRetinal Diseases and Treatments