Litcius/Paper detail

Hallmarks of CD8+ T cell dysfunction are established within hours of tumor antigen encounter before cell division

Michael Rudloff, Paul Zumbo, Natalie R. Favret, Jessica J. Roetman, Carlos R. Detrés Román, Megan M. Erwin, Kristen A. Murray, Sriya Jonnakuti, Friederike Dündar, Doron Betel, Mary Philip

2023Nature Immunology128 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEpigeneticsCD8ImmunologyT cellChromatinCell divisionChromatin remodelingTumor progressionCytotoxic T cellCancer researchAntigenCell biologyCellCancerImmune systemGeneticsIn vitroDNAGeneImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology