Highly selective fluorescent turn-on–off sensing of OH<sup>−</sup>, Al<sup>3+</sup> and Fe<sup>3+</sup> ions by tuning ESIPT in metal organic frameworks and mitochondria targeted bio-imaging
Soumya Bhowal, Arijit Ghosh
Abstract
ions. The study further demonstrates the MOF's behaviour in cellular medium by subjecting it to live cell confocal microscopy. Along with a bio-compatible nature the MOF exhibited successful accumulation inside the mitochondria of MCF7 cancer cells, which defines it as a significant bio-marker. Therefore the present work successfully represents the multidisciplinary nature of Zn-DHNDC MOFs, primarily in sensing and biomedical studies.
Topics & Concepts
FluorescenceChelationMetal ions in aqueous solutionChemistryQuenching (fluorescence)IonMetal-organic frameworkPhotochemistryIntramolecular forceMetalInorganic chemistryPhysical chemistryStereochemistryAdsorptionOrganic chemistryQuantum mechanicsPhysicsMetal-Organic Frameworks: Synthesis and ApplicationsMolecular Sensors and Ion DetectionLuminescence and Fluorescent Materials